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Dr. Abhishek Sahu


Assistant Professor

Department of Biotechnology

NIPER Hajipur, Hajipur, Vaishali,Bihar PIN – 844102, India

eMail: asahu@niperhajipur.ac.in



Faculty CV

Academics

  • Ph.D. (Biotechnology) – Indian Institute of Technology Guwahati (IIT Guwahati), 2009
  • B.Tech (Biotechnology) – West Bengal University of Technology (WBUT), 2005

Experience

• December 2021  – Present          Assistant Professor
                                                             Department of Biotechnology
                                                             NIPER Hajipur
                                                             Hajipur, India.
 
• March 2014 – December 2021     Research Fellow (Research Assistant Professor)
                                                              School of Materials Science and Engineering,
                                                              Gwangju Institute of Science and Technology (GIST)
                                                              Gwangju, Republic of Korea.
 
• October 2010 – May 2013            Post-Doctoral Researcher
                                                             School of Materials Science and Engineering,
                                                             Gwangju Institute of Science and Technology (GIST),
                                                             Gwangju, Republic of Korea.
 
• November 2009 – September 2010     Post-Doctoral Researcher
                                                                       Institute of Biomedical Engineering (INEB),
                                                                       Faculty of Engineering University of Porto (FEUP),

Research Areas

  • Nanozyme and their biomedical application
  • Polymer-antioxidant/drug conjugates
  • Novel Biomaterials

Selected Research Publications
PUBLICATIONS                                                                   

  1. Min, A. Sahu,S.H. Jeon, and G. Tae. Emerging drug delivery systems with traditional routes – A roadmap to chronic inflammatory diseases.Advanced Drug Delivery Reviews203, 115119, 2023. [IF: 16.1]
  2. Sahu*, K. Min*, K. Kwon and G. Tae. Self-assembled hemin-conjugated heparin with dual-enzymatic cascade reaction activities for acute kidney injury.Carbohydrate Polymers316, 121088, 2023. [*Equal contribution] [IF: 11.2]
  3. A.A. Abdelaziz, A. Sahu and P. Ramalingam. Pentacyclic triterpenoids from the stem of Grewia bracteata Roth demonstrate promising inhibition on tumour cells. Natural Product Research (In Press), 2023. [IF: 2.488]
  4. Kwon, J. Jung, A.Sahu and G. Tae. Nanoreactor for cascade reaction between SOD and CAT and its tissue regenerationeffect. Journal of Controlled Release 344, 160-172, 2022.[Selected as a Front Cover article][IF: 10.8]
  5. Sahu*, J. Jeon*, M.S. Lee, H.S. Yang and G. Tae. Nanozyme impregnated mesenchymal stem cells for hepatic ischemia-reperfusion injury alleviation. ACS Applied Materials and Interfaces 13(22), 25649-25662, 2021. [*Equal contribution] [Selected as a Supplementary Cover article][IF: 9.5]
  6. Sahu*, J. Jeon*, M.S. Lee, H.S. Yang and G. Tae. Antioxidant and anti-inflammatory activities of Prussian blue nanozyme promotes full-thickness skin wound healing. Materials Science and Engineering C119,111596,2021. [*Equal contribution] [IF: 8.457]
  7. Sahu, K. Min, J. Jeon, H.S. Yang and G. Tae. Catalytic nanographene oxide with hemin for enhanced photodynamic therapy. Journal of Controlled Release 326, 442-454, 2020. [IF: 10.8]
  8. Sahu, I. Kwon and G. Tae. Improving cancer therapy through the nanomaterials-assisted alleviation of hypoxia. Biomaterials 228, 119578, 2020. [IF: 14]
  9. Kim*, A. Sahu*, Y. Hwang, G.B. Kim, G.H. Nam, I.S. Kim, I.C. Kwon and G. Tae. Targeted delivery of anti-inflammatory cytokine by nanocarrier reduces atherosclerosis in Apo E−/−mice.Biomaterials 226, 119550, 2020. [*Equal contribution] [IF: 14]
  10. I. Choi, A. Sahu, F.R. Wurm and S-M. Jo. Magnetoliposomes with size controllable insertion of magnetic nanoparticles for efficient targeting of cancer cells. RSC Advances 9, 15053-15060, 2019. [IF: 3.9]
  11. I. Choi, Y. Hwang, A. Sahu, K. Min, D.K. Sung, J.H. Chang and G. Tae. An injectable and physical levan-based hydrogel as a dermal filler for soft tissue augment. Biomaterials Science, 6, 2627-2638, 2018. [IF: 6.6]
  12. Sahu, Y.M Hwang, C. Vilos, J.M. Lim, S.H. Kim, W.I. Choi and G. Tae. A novel alendronate functionalized nanoprobe for simple colorimetric detection of cancer-associated hypercalcemia.Nanoscale 10, 13375-13383, 2018. [IF: 6.7] (Selected asBack Cover)
  13. Sahu, W.I. Choi and G. Tae.Recent progress in the design of hypoxia-specific nano drug delivery systems for cancer therapy.Advanced Therapeutics, 1, 1800026, 2018.[IF: 4.6] [Invited Review]
  14. Gwon, E.J. Jo, A. Sahu, J.Y. Lee, G. Tae and M.G. Kim. Improved near infrared-mediated hydrogel formation using diacrylated Pluronic F127-coated upconversion nanoparticles. Materials Science and Engineering C 90, 77-84,2018.[IF: 8.457]
  15. Kim, A. Sahu, G.B. Kim, G.H. Nam, W. Um, S.J. Shin,Y.Y. Jeong, I.S. Kim, K. Kim, I.C. Kwon and G. Tae. Comparison of in vivo targeting ability between cRGD and collagen-targeting peptide conjugated nano-carriers for atherosclerosis.Journal of Controlled Release 269,337-346, 2018. [IF: 10.8]
  16. Sahu, M. Kim, J. Ryu, J.G. Son, E. Lee, D.Y. Noh and G. Tae. Nanographene oxide as a switch for CW/pulsed NIR laser triggered drug release from liposomes.Materials Science and Engineering C 82, 19-24, 2018. [IF: 8.457]
  17. I. Choi, A. Sahu, C. Vilos, N. Kamaly, S.M. Jo, J.H. Lee and G. Tae. Bioinspired heparin nanosponge prepared by photo-crosslinking for controlled release of growth factors. Scientific Reports 7, 14351,2017. [IF: 4.996]
  18. I. Choi, B. Yameen, C. Vilos, A. Sahu, S.M. Jo, D. Sung andG. Tae. Optimization of fibrin gelation for enhanced cell seeding and proliferation in regenerative medicine applications. Polymers for Advanced Technologies 28, 124-129, 2017. [IF: 3.4]
  19. Sahu,J.H. Lee, H.G. Lee, Y.Y. Jeong and G. Tae. Prussian blue/serum albumin/indocyanine green as a multifunctional nanotheranostic agent for bimodal imaging guided laser mediated combinatorial phototherapy. Journal of Controlled Release236, 90-99,2016. [IF: 11.467]
  20. H. Lee, A. Sahu, W.I. Choi, J.Y. Lee and G. Tae. ZOT-derived peptide and chitosan functionalized nanocarrier for oral delivery of protein drug. Biomaterials 103, 160-169, 2016. [IF: 14]
  21. I. Choi*, A. Sahu*, C. Vilos, J.H. Lee, S. Kim, Y.K. Hong, D. Sul, S. Hwang, S.H. Lee andG. Tae. Chitosan functionalized thermosponge nano-carriers for prolonged retention and local delivery of chymopapain at the nucleus pulpous in porcine discs ex vivo.RSC Advances6, 90967-90972,2016.[*Equal contribution] [IF: 3.9]
  22. Jang, J.H. Lee, A. Sahu and G. Tae. Synergistic effect of folate and RGD dual ligand of nanographene oxide on tumor targeting and photothermal therapy in vivo. Nanoscale 7(44), 18584-18594, 2015. [IF: 6.7]
  23. H. Lee*, A. Sahu*, C. Jang and G. Tae. The effect of ligand density on in vivo tumor targeting of nanographene oxide. Journal of Controlled Release 209, 219-228, 2015. [*Equal contribution] [IF: 10.8]
  24. Sahu, W.I. Choi, J.H. Lee and G. Tae. Graphene oxide mediated delivery of methylene blue for combined photodynamic and photothermal therapy. Biomaterials 34(26), 6239-6248, 2013. [IF: 15.304]
  25. C. Rodrigues, C.L. Salgado, A. Sahu, M.P. Garcia, M.H. Fernandes and F.J. Monteiro. Preparation and characterization of collagen-nanohydroxyapatite biocomposite scaffolds by cryogelation method for bone tissue engineering applications. Journal of Biomedical Materials ResearchPart A 101A(4), 1080-1094, 2013. [IF: 4.9]
  26. Sahu,W.I. Choi and G. Tae. A stimuli-sensitive injectable graphene oxide composite hydrogel. Chemical Communications 48(47), 5820-5822, 2012. [IF: 4.9] (Selected asInside Front Cover)
  27. I. Choi, A. Sahu,Y.H. Kimand G. Tae. Photothermal imaging and cancer therapy based on gold nanorods. Annals of Biomedical Engineering 40(2), 534-546, 2012. [IF: 3.8]
  28. Sahu, N. Kasoju and U. Bora. Encapsulation of curcumin in pluronic block-copolymer micelles for drug delivery applications. Journal of Biomaterials Applications 25(6), 619-639, 2011. [IF: 2.9]
  29. Sahu,P. Goswami and U. Bora. Microwave mediated rapid synthesis of chitosan. Journal of Materials Science: Materials in Medicine 20(1), 171-175, 2009. [IF: 3.7]
  30. Sahu, N. Kasoju and U. Bora. Fluorescence study of curcumin-casein micelle complexation and its application as drug nanocarrier to cancer cells. Biomacromolecules 9(10), 2905-2912, 2008. [IF: 6.2]
  31. Sahu, U. Bora, N. Kasoju and P. Goswami. Synthesis of novel biodegradable and self-assembling methoxy poly(ethylene glycol)–palmitate nanocarrier for curcumin delivery to cancer cells. Acta Biomaterialia4(6), 1752-1761, 2008. [IF: 9.7]
  32. S. Ali, N. Kasoju, A. Luthra, A. Singh, H. Sharanabasava, A. Sahu and U. Bora. Indian medicinal herbs as sources of antioxidants. Food Research International41(1), 1-15, 2008. [IF: 8.1]
  33. Bora, A. Sahu, A.P. Saikia, V.K. Ryakala and P. Goswami. Medicinal plants used by the people of Northeast India for curing malaria. Phytotherapy Research 21(8), 800-804, 2007. [IF: 7.2]

PATENTS (Granted)

  1. Tae, A. Sahu,H.S. Yang and J. Jeon. Stem cell therapeutic agent for anti-inflammatory or damaged tissue regeneration containing Prussian blue nanoparticles, and method for manufacturing the same. Korea Intellectual Property Office, Patent registration noKR10-2476845,Granted/Registered on 07th December, 2022.
  2. Tae, A. Sahu,H.S. Yang and J. Jeon. Wound treatment and dressing material containing Prussian blue nanoparticles, and manufacturing method thereof. Korea Intellectual Property Office, Patent registration noKR10-2476844,Granted/Registered on 07th December, 2022.
  3. Tae, A. Sahu and J.H. Lee. Nanoparticles for diagnosis and treatment of tumors. United States Patent and Trademark Office, Patent registration no US10973933B2, Granted/Registered on 13th April, 2021.
  4. Tae, A. Sahu and M. Kim. Nanographene oxide integrated liposome complex and drug delivery system comprising the same.Korea Intellectual Property Office, Patent registration noKR10-2110424, Granted/Registered on 07th May, 2020.
  5. I. Choi, G. Tae and A. Sahu. Thiolated alendronate functionalized gold nanoparticle and method for manufacturing thereof, applications thereof. Korea Intellectual Property Office, Patent registration no KR10-1992401, Granted/Registered on 18th June, 2019.
  6. Tae, J.H. Lee, A. Sahu and C. Jang. Nanographene oxide labelled with several ligands and preparation method thereof. Korea Intellectual Property Office, Patent registration no KR10-1846456, Granted/Registered on 2nd April, 2018.
  7. Tae, A. Sahu and J.H. Lee. Nanoparticles for diagnosis and treatment of tumor. Korea Intellectual Property Office, Patent registration no KR10-1739046, Granted/Registered on 17th May, 2017.
  8. Tae and A. Sahu. Composition for hydrogel based on graphene oxide being injectable and sensitive to external stimuli, method for preparing hydrogel using the same, and method for in vivo gelation using the same. Korea Intellectual Property Office, Patent registration no KR10-1381826, Granted/Registered on 31st March, 2014.

PATENTS (Applied)

  1. Tae, A. Sahu,H.S. Yang and J. Jeon. Cell therapeutic agent for anti-inflammatory or damaged tissue regeneration comprising Prussian blue nanoparticles, and method for preparing the same. United States Patent and Trademark Office, Patent applicationpublicationUS20220265724,Date of application 07thJanuary, 2022.

PROJECT GRANT

  1. Ongoing
  2. Startup Research Grant (SRG)

Funding agency: SERB / DST Project title:Development of enzyme-mimicking polymeric nanomaterials for biomedical applications Role: Principal Investigator (PI) Sanctioned fund: INR 29.3 lakhs Duration:2 years (January 2023 to December 2024)